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This is a fascinating and important set of data which shows us where things are going, using OpenAI as a canary in the coal mine. The chatbot era is over, and agentic systems are coming to tasks beyond engineering. And skills show promise as a way to standardize AI use in firms.

— @emollick

Presented at #ASCO26: Among patients with previously treated metastatic pancreatic ductal adenocarcinoma, the RAS(ON) inhibitor daraxonrasib led to significantly longer overall survival and progression-free survival than chemotherapy. Full phase 3 RASolute 302 trial results:

— @NEJM

video

I just pushed a new paper to arXiv. I realized that a lot of my previous work on robust losses and nerf-y things was dancing around something simpler: a slight tweak to the classic Box-Cox power transform that makes it much more useful and stable. It's this f(x, λ) here:

— @jon_barron

Adam, a 9-yr old optimizer, is the go-to for training LLMs (eg, GPT-3, OPT, LLAMA). Introducing Sophia, a new optimizer that is 2x faster than Adam on LLMs. Just a few more lines of code could cut your costs from $2M to $1M (if scaling laws hold). https://t.co/GrMY600lLO 🧵⬇️

— @tengyuma

Another example: Take two glasses of equally sweet water and mix them together. Children of intermediate age think that the resulting solution will be sweeter than the originals! Similar results have been found for water temperature.

— @Chris_Said

Fintechs tends to have worse delinquency rates than banks in personal loans. Source: @JPMorganAM

— @SnippetFinance

@AlecStapp Isn't Japan somewhat unique since a significant amount of land (major cities esp) is "leasehold," held by the same families for generations. Lessors (users) build for short-term use, maybe a generation or 20 years before expected teardown, and Japan's population is shrinking:

— @RFrances2

weird charts

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